Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 4 2020 10 31 178 182 Marija Bjelobrk 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Slobodan Dodic 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Tatjana Miljkovic 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Golub Samardzija 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Ilija Bjeljac Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Dragana Dabovic Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Biljana Dodic Educons University, Sremska Kamenica, Serbia. Milenko Rosic 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Mila Kovacevic 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Aleksandar Redzek 1University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia. 2Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. Miklos Fabri Institute of Cardiovascular Diseases Vojvodina, Clinic of Cardiology, Sremska Kamenica, Serbia. 2019 08 23 2020 07 30 The most common cause of coronary artery aneurysms is atherosclerosis, which is associated with over 50% of all aneurysms diagnosed in adults. Although patients can be asymptomatic throughout their lives, giant coronary artery aneurysms can manifest themselves as myocardial infarction, aneurysmal rupture, and sudden cardiac death as well. Herein, we describe an asymptomatic patient with numerous risk factors and a positive cardiopulmonary exercise test who was admitted to the cardiology clinic for coronary angiography. A giant coronary artery aneurysm (3.0×2.0 cm in diameter) in the left anterior descending coronary artery and significant stenosis in both left and right coronary arteries were found. After discussing possible treatment options, the hospital’s heart team recommended the surgical resection of the aneurysm and double coronary artery bypass graft. Four years after the cardiac surgery, at the time of writing the current manuscript, the patient is still in good condition and with no symptoms. https://rhythm.tums.ac.ir/index.php/jthc/article/view/1130 https://rhythm.tums.ac.ir/index.php/jthc/article/download/1130/928