Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 9 2 2015 10 11 90 92 EN Alireza Rostamzadeh Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, Iran. Kamal Khademvatani Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, Iran. Yousef Rezaei Seyyed-al-Shohada Heart Center, Urmia University of Medical Sciences, Urmia, Iran. Nariman Sepehrvand National Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 11 2015 10 11 Right-sided heart thrombus is a life-threatening condition that necessitates immediate therapy. Detection of right-sided heart thrombus is usually via transthoracic echocardiography. Generally, thrombolysis is considered a treatment of choice, but there is currently no consensus about the optimal therapeutic choice. We present a case of multiple right atrial thrombi with concurrent mobile and broad-based in situ thrombi in a patient with a history of chronic obstructive pulmonary disease, which was completely resolved by thrombolysis following a failed Heparin infusion. The patient was sent home in good clinical condition and was stable at 3 months' follow-up. https://rhythm.tums.ac.ir/index.php/jthc/article/view/333 https://rhythm.tums.ac.ir/index.php/jthc/article/download/333/326