Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 10 1 2015 10 13 43 45 EN Ahmet Baris-Durukan Medicana International Ankara Hospital, Department of Cardiovascular Surgery, Ankara, Turkey. Hasan Alper-Gurbuz Medicana International Ankara Hospital, Department of Cardiovascular Surgery, Ankara, Turkey. Murat Tavlasoglu Diyarbakir Military Hospital, Department of Cardiovascular Surgery, Diyarbakir, Turkey. Halil Ibrahim-Ucar Medicana International Ankara Hospital, Department of Cardiovascular Surgery, Ankara, Turkey. Cem Yorgancioglu Medicana International Ankara Hospital, Department of Cardiovascular Surgery, Ankara, Turkey. 2015 10 13 2015 10 13 Global myocardial ischemia and ischemia-reperfusion injury are potential adverse events related with cardioplegic arrest. Beating heart surgery has avoided such complications and adapted to valve surgery following successful results published on myocardial revascularization. Difficulty in weaning from cardiopulmonary bypass may be lessened by using on-pump beating heart surgery for mitral valve interventions. Here we describe a 64-year-old male patient with severe mitral regurgitation and dilated cardiomyopathy. Beating heart mitral valve replacement surgery was performed without aortic cross-clamping through a right thoracotomy approach. We believe that, particularly in patients with poor left ventricular functions, beating heart mitral valve surgery may be advantageous https://rhythm.tums.ac.ir/index.php/jthc/article/view/363 https://rhythm.tums.ac.ir/index.php/jthc/article/download/363/356