Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 10 3 2015 12 17 152 155 EN Hamid Amoozgar Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Maryam Ahmadipoor Neonatology and Cardiac Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Ahmad Ali Amirghofran Cardiac Surgery Department, Shiraz University of Medical Sciences, Shiraz, Iran. 2015 12 17 2015 12 17 Total anomalous pulmonary venous connection (TAPVC) is an anomaly in which the pulmonary veins are directly connected to one of the systemic veins or drain into the right atrium. Management of pulmonary hypertension after the total correction of this congenital cardiac anomaly is very important. Unligation of the vertical vein in the supracardiac type of this anomaly can be a draining pathway for the prevention of postoperative pulmonary hypertension crisis. Late onset transcatheter closure of the unligated vertical vein after a decrease in pulmonary pressure with the Amplatzer vascular plug type 1can prevent residual left-to-right shunting. Here we describe two patients who previously underwent surgical correction of supracardiac TAPVC and their vertical veinwas partially ligated due to severe pulmonary hypertension. Consequently, because of increased left-to-right shunting in the follow-up period, transcatheter occlusion of the vertical vein was done for them and this procedure seemed safe and less invasive compared to the surgical approach.At 2 years'follow-up, there was marked pulmonary artery pressure and clinical improvement. https://rhythm.tums.ac.ir/index.php/jthc/article/view/435 https://rhythm.tums.ac.ir/index.php/jthc/article/download/435/385