Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 13 1 2018 02 24 18 23 EN Sima Rafieyian Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Shahla Roodpeyma Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Kourosh Vahidshahi Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Alireza Moghadasi Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2016 04 13 2017 06 21 Background: Tissue Doppler imaging yields useful information about regional myocardial function. The purpose of this study was to investigate myocardial function by strain and strain rate in a group of patients with congenital heart disease (CHD) before and after cardiac surgery. Methods: Three consecutive tissue Doppler echocardiographic examinations were performed on 25 patients with CHD, who underwent open-heart surgery. The study was conducted from April 2013 to April 2014 in a university hospital, and the assessments were done 1 day before and 1 week and 1 month after surgery. The effects of demographic variables, types of anomalies, and cardiopulmonary bypass factors on strain were evaluated. Results: The study population comprised 13 female and 12 male patients at a mean age of 9.4 ± 9.8 years. Compared to the preoperative data, repeated measurements of strain in 9 segments of the ventricles showed a significant reduction 1 week after surgery, followed by a significant augmentation 1 month  postoperatively (p value = 0.001 for all 9 segments). The reduction in strain at the middle segment of the left ventricular free wall was significant in the cyanotic patients (p value = 0.037). The increase in strain at the middle segment of the septum and the right ventricular basal and middle segments was significant (p value = 0.021, p value = 0.015, and p value = 0.021, respectively) in the patients with a shorter pump time. Conclusion: Our patients experienced an early decline in myocardial function after cardiac surgery, but their myocardium recovered its contractility gradually. https://rhythm.tums.ac.ir/index.php/jthc/article/view/532 https://rhythm.tums.ac.ir/index.php/jthc/article/download/532/630