Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 12 1 2017 03 05 32 34 EN Mahmood Hosseinzadeh Maleki Atherosclerosis and Coronary Artery Research Center, Birjand University of Medical Sciences, Birjand, Iran. Moein Aboobakri Makouei Atherosclerosis and Coronary Artery Research Center, Birjand University of Medical Sciences, Birjand, Iran. Farbod Hatami Atherosclerosis and Coronary Artery Research Center, Birjand University of Medical Sciences, Birjand, Iran. Reza Zeinabadi Noghabi Atherosclerosis and Coronary Artery Research Center, Birjand University of Medical Sciences, Birjand, Iran. 2017 02 11 2017 02 11 Primary cardiac sarcomas are rare clinical entities with an incidence rate of 0.0001% in collected autopsy series and are regarded as very aggressive tumors. We herein describe a 21-year-old woman presenting with syncope, dyspnea, and abdominal distention. She suffered from massive ascites, plural effusion, and liver congestion demonstrated by abdominal sonography and chest X-ray. Transthoracic echocardiography revealed a heterogeneous solid mass located in the right atrium; therefore, the patient underwent radical surgical excision of the tumor and 3 cycles of adjuvant chemotherapy.  Fifteen months after surgery, she was having a favorable life quality without any evidence of recurrence. https://rhythm.tums.ac.ir/index.php/jthc/article/view/676 https://rhythm.tums.ac.ir/index.php/jthc/article/download/676/500