Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 13 4 2018 10 15 186 190 EN Ali Mohammad Haji Zeinali Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Yaser Jenab Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Hamid Ariannejad Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Seyed Ebrahim Kassaian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Alidoosti Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Hassan Aghajani Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Reza Zafarghandi Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2018 05 17 2018 10 20 Iliofemoral deep vein thrombosis (IFDVT) is a potentially devastating condition comprising a quarter of all cases of lower extremity DVT. It can lead to serious consequences such as pulmonary embolism, limb malperfusion, and post-thrombotic syndrome (PTS), which is a chronic sequela of IFDVT. We herewith present 18 IFDVT cases managed with catheter-directed thrombolysis at our hospital. Nine of these patients underwent stenting of the involved iliac veins. The remaining 9, who did not receive stenting, had a residual stenosis of more than 50% in the common femoral or iliac veins following the procedure. Based on a final residual stenosis of less than 50% in the iliac veins, we had 9 successful (patients with stenting) and 9 unsuccessful procedures (patients without stenting). In subsequent follow-ups at a median follow-up of 39.5 months, using the Villalta score, while only 2 out of the 9 patients who underwent stenting suffered PTS, 4 patients among the other 9 patients comprising the non-stenting group developed PTS. Our results support the notion that stenting might have a role in decreasing the PTS risk in patients undergoing catheter-directed thrombolysis. https://rhythm.tums.ac.ir/index.php/jthc/article/view/887 https://rhythm.tums.ac.ir/index.php/jthc/article/download/887/803