Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 14 2 2019 03 14 85 89 EN Ahmet Korkmaz Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara, Turkey. Havva Gürsoy Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara, Turkey. Mehmet İleri Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara, Turkey. Özgül Elalmış Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara, Turkey. Ümit Güray Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara, Turkey. 2018 08 19 2018 12 31 Transcatheter aortic valve implantation (TAVI) has shown favorable outcomes in patients with severe symptomatic aortic valve stenosis who are at high surgical risk or who are unsuitable candidates for open-heart surgery. However, concerns exist over treating patients who have undergone previous mitral valve surgery due to the potential interference between the mitral prosthetic valve or ring and the TAVI device. In this case report, we present a case in which a patient with symptomatic severe aortic stenosis and previous mechanical mitral valve replacement was successfully treated with TAVI using a Portico valve, which is under-researched. https://rhythm.tums.ac.ir/index.php/jthc/article/view/952 https://rhythm.tums.ac.ir/index.php/jthc/article/download/952/837