Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 127 130 Carlos Mestres Andrea Colli Department of Cardiac Surgery, Hospital Universitari “Germans Trias i Pujol”, Badalona, Barcelona, S Jose Aramendi Department of Cardiovascular Surgery, Hospital de Cruces, Barakaldo, Bizcaia, Spain. 2015 10 03 https://rhythm.tums.ac.ir/index.php/jthc/article/view/93 https://rhythm.tums.ac.ir/index.php/jthc/article/download/93/91

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 131 140 Ali Azizzadeh Memorial Hermann Hospital-Heart & Vascular Institute, The University of Texas at Houston Medical Sch Anthony Estrera Memorial Hermann Hospital-Heart & Vascular Institute, The University of Texas at Houston Medical Sch Charles Miller Memorial Hermann Hospital-Heart & Vascular Institute, The University of Texas at Houston Medical Sch Hazim Safi Memorial Hermann Hospital-Heart & Vascular Institute, The University of Texas at Houston Medical Sch 2015 10 03 Over the last 50 years, significant progress has been made in the surgical repair of thoracoabdominal aortic aneurysms (TAAA).  Improvements in perioperative care and surgical techniques have resulted in reductions in complication and mortality rates. Adjunctive use of distal aortic perfusion and cerebrospinal fluid drainage has been especially helpful, reducing the incidence of neurological deficits to 2.4%. Current research is aimed at improving organ preservation. This review focuses on the current diagnosis and management of TAAA. https://rhythm.tums.ac.ir/index.php/jthc/article/view/94 https://rhythm.tums.ac.ir/index.php/jthc/article/download/94/92

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 141 144 Ali Akbar Zeinaloo Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Seyyed Mahmoud Meraji Shaheed Rajayee Cardiovascular Center, Iran University of Medical Sciences, Tehran, Iran. Keyhan Sayadpour Zanjani Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Reza Mirzaaghayan Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 03 Background: Closure of patent ductus arteriosus (PDA), ventricular septal defect (VSD) and atrial septal defect (ASD) can be done surgically or by device. This study was designed to compare the total cost of surgical or device closures of PDA, ASD or VSD for Iranian patients. Methods: This is a cross-sectional study, conducted from January 1, 2005 until January 1, 2006 in two large heart centers of Tehran. The study population consisted of 91 patients with isolated PDA, ASD or VSD who underwent either surgical or device closure.   Results: PDA device closure either with the Amplatzer device or coil was less costly than that via surgery. VSD closure with the Amplatzer device was more costly (17.6%). Although ASD closure was also more expensive (15.4%), the difference was not statistically significant. Conclusion: It can be concluded that PDA closure is cheaper than surgery in Iran. ASD and VSD device closures are more expensive, but the added cost can be affordable in view of the advantages of device closure.   https://rhythm.tums.ac.ir/index.php/jthc/article/view/95 https://rhythm.tums.ac.ir/index.php/jthc/article/download/95/93

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 145 150 Hakimeh Sadeghian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mojtaba Salarifar Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Abbas Ali Karimi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mehrab Marzban Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Kyomars Abbasi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Masoumeh Lotfi-Tokaldany Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mahmood Sheikhfathollahi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Majd Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Sirous Jahangiri Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Seyed Hesameddin Abbasi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 03 Background: We compared the outcomes in patients with a low ejection fraction (EF) and multivessel coronary artery disease (CAD) who either underwent coronary artery bypass grafting (CABG) or received medical treatment (MT) after a viability study via dobutamine stress echocardiography (DSE). Methods: We considered patients with CAD and left ventricular ejection fraction (LVEF) <40% who were referred for DSE, and enrolled 106 patients (89% male, mean age: 55.8±9.7 years) with ≥4 viable segments. According to DSE, all the 106 patients were suitable for revascularization. We compared the outcomes between the patients who underwent CABG and those who received MT at a mean follow-up time of 8 months. Results: Both groups had similar baseline characteristics and rest EF. Thirty-three (31.1%) patients underwent CABG and 73 (68.9%) received MT. There was no significant difference between the CABG and MT groups in terms of mortality rate (9.1% vs. 11.0 %) and improvement in New York Heart Association functional class at follow-up. In the CABG group, patients with LVEF ≤25% had higher mortality compared to patients with LVEF >25% (100% vs. 40%, P< 0.05). Conclusion: The patients with CAD and a low EF had the same survival rate after both CABG and MT at mid-term follow-up. Long-term follow-up is needed to show the survival benefit of CABG in such patients with an acceptable extent of viable myocardium.  https://rhythm.tums.ac.ir/index.php/jthc/article/view/96 https://rhythm.tums.ac.ir/index.php/jthc/article/download/96/94

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 151 156 Mostafa Behjati Ardakani Afshar Hospital, Yazd University of Medical Sciences, Yazd, Iran. Sayed khalil Forouzannia Afshar Hospital, Yazd University of Medical Sciences, Yazd, Iran. Majid Dehghani Afshar Hospital, Yazd University of Medical Sciences, Yazd, Iran. Mohammad Hassan Abdollahi Afshar Hospital, Yazd University of Medical Sciences, Yazd, Iran. 2015 10 03 Background: The transcatheter closure of patent ductus arteriosus has advanced rapidly with improvements in device designs. The aim of this study was to analyze the safety, efficacy, and early and intermediate follow-up results of the percutaneous closure of persistent ductus arteriosus (PDA) with the Amplatzer ductal occluder (ADO) in children.   Methods: Between May 2004 and March 2007, fifty patients between 7 months and 20 years of age underwent the transcatheter closure of PDA, using the ADO. The mean PDA diameter at its narrowest segment (pulmonary end) was 7.35±2.57 mm (range: 4 to 16mm). Follow-up evaluations were performed via echocardiography at 24 hours, and 1, 3, 6, and 12 months and then yearly after implantation. Results: Successful immediate occlusion of PDA was achieved in 42 (84%) of the 50 cases.  In 5 cases, there were trivial intraprosthetic residual shunts. In addition, there was a small residual shunt in one case, left pulmonary artery narrowing in one case, and embolization of the device immediately after the procedure in one case. At 24 hours, color Doppler flow mapping revealed complete closure in all except one case with a small shunt. At 3 months’ follow-up, occlusion was complete in all the patients. At a median follow-up of 17 months (range: 3 months to 32 months), all the patients had complete closure. Conclusion: We conclude that although the transcatheter closure of PDA using the ADO is a highly effective and safe treatment for most patients, several complications including embolization and left pulmonary artery narrowing may occur in certain cases.    https://rhythm.tums.ac.ir/index.php/jthc/article/view/97 https://rhythm.tums.ac.ir/index.php/jthc/article/download/97/95

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 157 162 Mohammad Yusef Aarabi Moghaddam Shaheed Rajaie Cardiovascular Center, Iran University of Medical Sciences, Tehran, Iran. Seyed Mohammad Dalili Shaheed Rajaie Cardiovascular Center, Iran University of Medical Sciences, Tehran, Iran. Zahra Emkanjoo Shaheed Rajaie Cardiovascular Center, Iran University of Medical Sciences, Tehran, Iran. 2015 10 03 Background: This study was done to assess the efficacy and adverse effects of the different doses of adenosine in the pediatric age group with respect to multiple patient variables.  Methods: Over a period of 1 year, 86 occasions of supraventricular tachycardia (SVT) were treated with adenosine in 81 infants and children aged between 18 days and 12 years (median of 1.3 years, SD=3). Adenosine efficacy was evaluated in terms of the patients’ demographics, SVT rate, electrocardiogram characteristics, and route of drug administration. Results: The dose of 50μg/kg was effective only in 24% of the SVT cases, and the additional doses of 100μg/kg, 150μg/kg, and 200μg/kg were effective in another 29% of the cases. The drug efficacy was higher in the infants than that in the older children. There were no predictors other than age for the estimation of the efficacy of the drug. Conclusion: Our findings showed that the current recommended doses of adenosine are ineffective in the vast majority of children and infants with SVT. No patient-related factor other than age seems to affect the efficacy of the drug.   https://rhythm.tums.ac.ir/index.php/jthc/article/view/98 https://rhythm.tums.ac.ir/index.php/jthc/article/download/98/96

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 163 168 Mohammad Ali Boroumand Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Maryam Sotoudeh Anvari Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mehrdad Sheikhvatan Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Soheil Saadat Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Seyed Hesameddin Abbasi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mahmood Sheikhfathollahi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 03 Background: The potential role of lipoprotein (a) changes and also inflammation in coronary artery disease (CAD) have rendered these processes one of the most interesting objects of study in patients affected by type 2 diabetes mellitus. The aim of the current study was to evaluate lipoprotein (a) and other lipid profiles and also C-reactive protein (CRP) as the predictors of cardiovascular disease severity in non-insulin dependent diabetic subjects in comparison with non-diabetic CAD patients.  Methods: Between June and September 2004, 372 patients with CAD were enrolled at Tehran Heart Center. Non-insulin dependent diabetics accounted for 102 of the cases, and the remaining 270 were non-diabetics. The severity of CAD was evaluated using the Gensini score, and the effect of patient variables such as serum lipid concentrations and CRP on CAD severity in the diabetics was investigated and compared with that of the non-diabetics. Results: The mean of the Gensini score, CRP, and serum concentrations of all the lipid profiles were similar between the diabetic and non-diabetic patients. In the diabetic group, a high CRP concentration (β=0.200, Rs= 0.040; P=0.046) was effective on the Gensini score, whereas lipoprotein (a) and lipid profiles did not influence CAD severity. In the non-diabetics, no significant relationships were found between the Gensini score and all the studied laboratory indices. Conclusion: A high CRP level is an important predictor of the severity of CAD in diabetic patients with CAD. https://rhythm.tums.ac.ir/index.php/jthc/article/view/99 https://rhythm.tums.ac.ir/index.php/jthc/article/download/99/97

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 3 3 2008 07 15 169 172 Seyedeh Seddigheh Fatemi Bu-Ali Research Institute, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran. Mehdi Hasanzadeh Ghaem Hospital, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran. Arman Arghami Ebne Sina Hospital, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran. Mohammad Reza Sargolzaee Ebne Sina Hospital, Mashhad University of Medical Sciences (MUMS), Mashhad, Iran. 2015 10 03< Afrasyab Altaf Cardiology Department, Rehman Medical Institute, Peshawar, Pakistan. 2018 03 04 2019 03 25 Air inside the pericardial cavity is called “pneumopericardium”, which is a rare complication of pericardiocentesis. Pneumopericardium may resolve spontaneously or can complicate into tension pericardium, requiring urgent aspiration. We herein describe a 55-year-old man with pericardial effusion who underwent pericardiocentesis. The patient was completely asymptomatic after the procedure. Chest radiograph and computed tomography scan accidentally detected pneumopericardium, which was subsequently complicated by atrial fibrillation and necessitated pharmacological cardioversion. We found no case of asymptomatic pneumopericardium complicated by atrial fibrillation after pericardiocentesis in our literature review. Clinicians and cardiologists should do a post pericardiocentesis chest X-ray to diagnose pneumopericardium and prevent the catastrophic complications of tension pneumopericardium. https://rhythm.tums.ac.ir/index.php/jthc/article/view/857 https://rhythm.tums.ac.ir/index.php/jthc/article/download/857/851

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 14 3 2019 06 15 138 140 Seifollah Abdi Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran. Mohammad Reza Baianati Madaen Hospital, Tehran Iran. Mahmood Momtahen Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran. Bahram Mohebbi Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran. 2019 01 05 2019 04 10 Intramural esophageal dissection is a condition that typically presents with chest pains and may be associated with hematemesis, odynophagia, and hematemesis. The role of antiplatelet/anticoagulant agents in the development of intramural esophageal hematoma is controversial. The management of intramural esophageal dissection is generally conservative with low mortality and morbidity. The case described here is a 66-year-old woman who presented with chest pains, odynophagia, and dysphagia 1 month after percutaneous coronary intervention while taking AS