Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 143 148 Matko Marusic Croatian Medical Journal, University of Split School of Medicine, Split, Croatia. Ana Marusic Croatian Medical Journal, University of Split School of Medicine, Split, Croatia. 2015 10 03 - https://rhythm.tums.ac.ir/index.php/jthc/article/view/133 https://rhythm.tums.ac.ir/index.php/jthc/article/download/133/131

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 149 158 Habibollah Saadat Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Roxana Sadeghi Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Mohammad Reza Motamedi Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Mohammad Hasan Namazi Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Morteza Safi Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Hosein Vakili Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Kambiz Sadaghiani Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran Zahra Saadat Cardiovascular Research Center, Shaheed Beheshti University of Medical Sciences (SUMS), Tehran, Iran 2015 10 03 The clinical and economic importance of heart failure is widely recognized.  The incidence of heart failure is on the increase, particularly with the aging of the population around the world.  It is time for a paradigm shift in heart failure management. Alternative non-pharmacological strategies to remodel the failing ventricle will shape a major portion of heart failure therapy in the decade ahead. Exposure to heat is widely used as a traditional therapy in many cultures.  In this paper, we will review recent data that suggest thermal therapy may be helpful as an adjunctive non-pharmacological treatment for heart failure. https://rhythm.tums.ac.ir/index.php/jthc/article/view/134 https://rhythm.tums.ac.ir/index.php/jthc/article/download/134/132

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 159 164 Soheil Saadat Sina Trauma Research Center (STRC), Tehran University of Medical Sciences, Tehran, Iran. Saeed Sadeghian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Saeed Sadeghian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Reza Hamidian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Ali Najafi Air Quality Control Company, Tehran Municipality, Tehran, Iran. 2015 10 03 Background: There are some reports on the association between air pollution and myocardial infarction, arrhythmia, and mortality due to cardiac problems in susceptible individuals. We aimed to evaluate the association of air pollution and the emergency visits due to cardiovascular diseases, in a specialized heart hospital in Tehran. Methods: The study design was cross-sectional. Patients admitted to the emergency ward of Tehran Heart Center were consecutively included. Records of meteorological data for the study period were obtained from Air Quality Control Company that monitors the concentration of air pollutants through its several stations including one near to Tehran Heart Center. The principal component analysis was used to examine the association between daily air pollution level and the number of patients admitted as a result of unstable angina, myocardial infarction, and arrhythmia. Results: The principal component score -reflecting the daily air pollution level- was higher on the admission date of the patients who died in hospital compared to that of the patients who discharged alive from the hospital and the difference was statistically significant. After adjustment for the effect of age, sex, smoking, hypertension, hyperlipidemia and diabetes, a statistically significant relationship between principal component score and the unstable angina and arrhythmia was detected in patients referred to the emergency department. Conclusion: Air pollution was associated with the unstable angina and arrhythmia in patients referred to the emergency department of Tehran Heart Center, adjusted for the effect of other risk factors. https://rhythm.tums.ac.ir/index.php/jthc/article/view/135 https://rhythm.tums.ac.ir/index.php/jthc/article/download/135/133

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 165 170 Maryam Esmaeilzadeh Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran, Iran. Azadeh Sadatnaseri Sina General Hospital, Tehran University of Medical Sciences, Tehran, Iran. Feridoun Noohi Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran, Iran. Majid Maleki Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran, Iran. Anita Sadeghpour Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran, Iran. Ahmad Mohebbi Shaheed Rajaei Cardiovascular Medical and Research Center, Tehran, Iran. 2015 10 03 Background: There is some evidence indicating improvement in myocardial performance after atrial septal defect closure, either device closure or surgical, but ventricular dyssynchrony has not been evaluated before and after surgical closure. The aim of this study was to evaluate ventricular mechanical dyssynchrony in patients with atrial septal defect before and after surgical closure. Methods: Twenty patients (mean age: 23±11years) with isolated secundum or sinus venosus type atrial septal defect, unsuitable for device closure, were evaluated before and after successful surgical closure. Interventricular and intraventricular dyssynchrony (using 6 basal and 6 mid-segmental models) were determined. Results: A significant reduction in the right atrial and right ventricular dimensions and the tricuspid regurgitation peak gradient was noted after atrial septal defect closure (3.6±0.54 cm versus 4.2±0.7, P=0.009; 3.5±0.29 cm versus 4.3±0.41, P=0.02; and 20.4±10.5 mmHg versus 35.3±6.5, P<0.002; respectively). There was no significant difference in the maximum difference in time-to-peak systolic velocity and the standard deviation of time-to-peak systolic velocity of the l2 left ventricular myocardial segments in the patients with atrial septal defect before and after surgical closure in comparison with the normal subjects (normal: 26±10.64 ms versus before closure: 21.0±33.9 versus after closure: 27±29.5, both P=0.68) and the left ventricular asynchrony index after atrial septal defect closure (normal: 14.9±8.7 versus before closure: 11.46±8.5 versus after closure: 18.12±13.6, both P=0.2). There was a significant positive relation between the tricuspid regurgitation peak gradient and the left ventricular asynchrony index (r=0.67, P=0.03) and an insignificant negative relation between the left ventricular ejection fraction and the asynchrony index before atrial septal defect closure (r=−0.53, P=0.11). No significant relation was found between the total asynchrony index and the atrial septal defect size, the degree of left-to-right shunt, and the tricuspid regurgitation peak gradient. Conclusion: There was no significant ventricular dyssynchrony in the patients with atrial septal defect before and after surgical closure. https://rhythm.tums.ac.ir/index.php/jthc/article/view/136 https://rhythm.tums.ac.ir/index.php/jthc/article/download/136/134

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 171 176 Siamak Sabour Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Marie Louise Bartelink Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Annemarieke Rutten Radiology Department, University Medical Center Utrecht, Utrecht, the Netherlands. Diederick E Grobbee Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Mathias Prokop Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Yvonne T van der Schouw Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Michiel L Bots Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the 2015 10 03 Background: Myocardial infarctions at different locations have been related to different sets of risk factors. This study was designed to examine the association between cardiovascular risk factors and specific coronary artery calcification (CAC). Methods: The study population comprised 573 postmenopausal women selected from a population-based cohort study. Established vascular risk factors were measured. The women underwent a multi detector-row computed tomography (16-MDCT) (Philips Mx 8000 IDT 16) to assess coronary calcium. The Agatston score was used to quantify coronary calcium. Logistic regression models were utilized to assess the relations. Results: The prevalence of coronary artery calcification (Agatston score>0) was 61.5% (n=348). CAC was most common in the left anterior descending (LAD) artery with a prevalence of 43.9%; and the rates of prevalence in the right coronary artery (RCA), the circumflex (LCX), the left main artery (LM), and the posterior descending artery (PDA) were 23.1%, 19.4%, 15.8%, and 0.3%, respectively. In the multivariate regression models, age was predominantly related to the calcification in the LAD and LCX, low density lipoprotein to calcification in the LAD, and cholesterol to the calcification of the RCA. Hypertension, systolic and diastolic blood pressures were related to the calcification of the LCX, whereas smoking was predominantly related to the calcification of both LAD and RCA. Finally, age, body mass index, and systolic blood pressure were significantly related to the calcification in the LM. Conclusion: Our findings showed that the consequences of elevated risk factor levels on the development of atherosclerosis appeared to be different across the segments of the coronary arteries. https://rhythm.tums.ac.ir/index.php/jthc/article/view/137 https://rhythm.tums.ac.ir/index.php/jthc/article/download/137/135

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 177 180 Tapas Pramanik Department of Physiology, Nepal Medical College, Kathmandu, Nepal. Puspak Regmi Nepal Medical College, Kathmandu, Nepal. Prakash Adhikari Ganesh Man Singh Memorial Academy of ENT and Head and Neck Studies, TU Teaching Hospital, Kathmandu, Paresh Roychowdhury Department of Physiology, Nepal Medical College, Kathmandu, Nepal. 2015 10 03 Background: Early detection of proneness to hypertension may help an individual to lead a healthy life by altering the life style. Subjects having the predisposing factors of hypertension tend to show higher and prolonged responsiveness to blood pressure following stress. Methods: Normotensive, non-smoking healthy sedentary male students and staff of Nepal Medical College (n=50, age group 18-35 years) participated in the study, conducted between May 2008 and June 2008. Participants with hypertensive parents, either or both, were considered volunteers from hypertensive families. The cold pressor test was carried out. The changes in blood pressure and heart rate among the volunteers of the hypertensive and normotensive families were compared using Student’s t-test. Results: In the present study, sympathetic stimulation exerted through the cold pressor test resulted in an elevation of blood pressure and heart rate in all the young male normotensive individuals. Blood pressure and heart rate returned to the baseline 5 minutes after the withdrawal of the stressor in the cases of the volunteers with no history of familial hypertension. On the other hand, the subjects whose parents, either or both, were reported to be hypertensive showed elevated diastolic blood pressure even 5 minutes after the withdrawal of the stressor. Conclusion: The present study revealed that the normotensive young male subjects who presented prolonged elevated diastolic pressure in response to sympathetic stimulation through the cold pressor test were prone to develop hypertension in the future.       https://rhythm.tums.ac.ir/index.php/jthc/article/view/138 https://rhythm.tums.ac.ir/index.php/jthc/article/download/138/136

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 4 3 2009 07 21 181 184 Shapour Shirani Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Madjid Shakiba Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Maryam Soleymanzadeh Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Ali Boroumand Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Seyed Hesameddin Abbasi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Maryam Sotoudeh Anvari Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Sirous Darabian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Maryam Esfandbod Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 ass 202 204 EN Feridoun Sabzi Cardiovascular Medical Center of Imam Ali Hospital, Kermanshah, Iran. Babak Nasiri Cardiovascular Medical Center of Imam Ali Hospital, Kermanshah, Iran. 2015 10 11 2015 10 11 Myxomas are the most common benign cardiac tumors. Myxomas are more common in the left heart chamber than the right side chamber. An extracardiac origin presenting as a right atrial mass is very rare. We present a case of myxoma originating in the superior vena cava (SVC) in a 24-year-old man, who underwent surgical resection. Preoperative two-dimensional echocardiography demonstrated a mass in the right atrium. Intraoperatively, the tumor was found to have originated from the SVC orifice. The tumor was excised from the SVC by opening the one-third proximal portion of the SVC. Pathological examination revealed a myxoma, and one-year follow-up showed no evidence of the recurrence of any tumors in the SVC. https://rhythm.tums.ac.ir/index.php/jthc/article/view/311 https://rhythm.tums.ac.ir/index.php/jthc/article/download/311/304

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 8 4 2015 10 11 205 209 EN Zohreh Annabestani Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Seyed Ebrahim Kassaian Tehran Heart Center, Tehran University of Medical Sciences, Iran. Mohammad Reza Mohajeri-Tehrani Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical SciencesInstitute, Tehran University of Medical Sciences, Tehran, Iran. Shahrzad Mohseni Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Sepideh Saroukhani Tehran Heart Center, Tehran University of Medical Sciences, Iran. Bagher Larijani Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 2015 10 11 2015 10 11 Hand ischemia is a rare complication of diabetes and some other chronic vascular diseases. Critical hand ischemia causes painful limbs and disability and requires urgent revascularization. There have been a few reports of successful trans-brachial percutaneous angioplasty in the upper extremity in the radial or ulnar artery. Herein, we report the results of the endovascular treatment of a 68-year-old diabetic patient with an ischemic hand ulcer due to the severe stenotic lesions of the infra-brachial arteries. The patient underwent successful angioplasty via the retrograde trans-femoral technique to avoid the drawbacks. At the first week of post-procedural follow-up, the patient’s finger was warm with a well–healing wound and reduced pain. In the next two months, he had no complaint of pain or active ulceration; the ulcer was well healed, and the hand was warm. The present case shows that history taking and physical examination should be followed by upper-extremity arteriography for the evaluation of hand ischemia. The trans-femoral approach enabled us to perform percutaneous catheterization for both diagnostic and interventional purposes. Not only is this strategy useful even for the severe stenotic disease of the distal parts of below-the-elbow arteries but also it avoids the unpleasant complications of antegrade brachial cannulation. https://rhythm.tums.ac.ir/index.php/jthc/article/view/312 https://rhythm.tums.ac.ir/index.php/jthc/article/download/312/305

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 8 4 2015 10 11 210 212 EN Hassan Teimouri Shahid Madani Hospital, Khoram Abad University of Medical Sciences, Khoram Abad, Iran Feridoun Sabzi Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. Samsam Dabiri Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran. 2015 10 11 2015 10 11 True saccular aneurysm is exceptional in coarctation of aorta in children. A 6-year-old girl with headache and systemic arterial hypertension referred to our center for cardiovascular evaluation. Physical examination revealed high blood pressure and weak lower extremity pulses. Two-dimensional and Doppler echocardiography and angiography demonstrated a saccular aneurysm of the descending aorta, 5×4 cm in size, associated with aortic coarctation. Aneurysmectomy was performed without cardiopulmonary bypass. The section of the aorta containing the coarctation and the aneurysm was resected and replaced with a 15-mm woven polyester graft. Histological examination revealed a thin walled aneurysm with hyalinosis changes and decreased elastic fibers. One-year echocardiographic follow-up revealed no gradient across of Dacron tube and hypertension decreased to normal level. https://rhythm.tums.ac.ir/index.php/jthc/article/view/313 https://rhythm.tums.ac.ir/index.php/jthc/article/download/313/306

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 8 4 2015 10 11 213 214 EN Farrokh Habibzadeh Director, NIOC Medical Education and Research Center, NIOC Health Organization Polyclinics, Eram Blvd, Shiraz, 71438, Iran. 2015 10 11 2015 10 11 No Abstract https://rhythm.tums.ac.ir/index.php/jthc/article/view/314 https://rhythm.tums.ac.ir/index.php/jthc/article/download/314/307

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 8 4 2015 10 11 215 216 EN Farideh Roshanali Day General Hospital, Tehran, Iran. Mohammad Hossein Mandegar Shariati General Hospital, Tehran University of Medical Sciences, Tehran, Iran. Bahieh Moradi Day General Hospital, Tehran, Iran. 2015 10 11 2015 10 11