Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 1 5 EN Hamid Bigdelian Department of Cardiovascular Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran. Mohsen Sedighi Department of Cardiovascular surgery, Chamran Heart Center, Isfahan University of Medical Sciences, Isfahan, Iran. 2018 09 25 2019 10 26 Background: The optimal surgical plan to correct the simple transposition of the great arteries (TGA) is the arterial switch operation (ASO). This study aimed to assess the outcomes of ASO in infants with simple TGA with a special focus on the time of surgery. Methods: This retrospective study enrolled 105 infants with simple TGA who underwent ASO and categorized them into 3 groups based on the time of repair: first week of life: Group A; second week of life: Group B; and third week of life: Group C. The endpoints, comprised of an assessment of pre- and postoperative outcomes, complications, and survival, were compared between the groups. Results: The mean age of the infants was 10.50±6.26 days, and 61 (58.1%) cases were male. The mean number of days on dopamine was 1.85±0.12 in Group A, 2.48±0.03 in Group B, and 2.67±0.08 in Group C (P<0.001). The mean number of days on epinephrine was 1.25±0.07 in Group B and 1.27±0.08 in Group C (P<0.001). The mean number of days on the ventilator was 3.52±0.20 in Group A, 4.56±0.24 in Group B, and 5.06±0.21 in Group C (P<0.001). The mean number of days of ICU stay was 6.69±0.21 in Group A, 8.46±0.57 in Group B, and 9.70±0.64 in Group C (P<0.001). The infants in Group A had a greater survival rate (97.0%) than those in Group B (94.1%) and Group C (78.4%) (P=0.042). Conclusion: ASO in infants with simple TGA can be done within the first week of life with satisfactory outcomes and survival. https://rhythm.tums.ac.ir/index.php/jthc/article/view/965 https://rhythm.tums.ac.ir/index.php/jthc/article/download/965/884

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 31 34 Nevri̇ye Salman Department of Anesthesia and Reanimation, SBU Yüksek İhtisas Ankara Research and Training Hospital, Ankara, Turkey. Sınan Kocabeyoğlu Department of Cardiovascular Surgery, SBU Yüksek İhtisas Ankara Research and Training Hospital, Ankara, Turkey. Ülkü Sabuncu Department of Anesthesia and Reanimation, SBU Yüksek İhtisas Ankara Research and Training Hospital, Ankara, Turkey. Ümit Kervan Department of Cardiovascular Surgery, SBU Yuksek Ihtisas Ankara Research and Training Hospital, Ankara, Turkey. Mustafa Paç Department of Cardiovascular Surgery, SBU Yüksek İhtisas Ankara Research and Training Hospital, Ankara, Turkey. Ayşegül Özgök Department of Anesthesia and Reanimation, SBU Yüksek İhtisas Ankara Research and Training Hospital, Ankara, Turkey. 2019 01 28 2019 07 23 The gold standard treatment for end-stage heart failure is heart transplantation; however, the rate of transplantation remains inadequate because of the paucity of organ donation. The left ventricular assist device (LVAD) has been used as a bridge therapy before transplantation. The LVAD is being used increasingly because it reduces mortality despite the accompanying morbidities. Therefore, the anesthetic management of LVAD-related morbidities is important and requires experience and knowledge. Herein, we describe a 60-year-old male patient with an LVAD with complaints of right hemiparesis, dysphasia, and facial paralysis. We aim to present the anesthetic management of a patient with intracranial hemorrhage who underwent LVAD exchange due to thrombosis. https://rhythm.tums.ac.ir/index.php/jthc/article/view/1031 https://rhythm.tums.ac.ir/index.php/jthc/article/download/1031/889

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 04 12 39 40 Timoor Etemad Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Narges Shahbazi Department of Pathology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Ali Hosseinsabet Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Khalil Forozannia Department of Cardiovascular Surgery, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. 2019 01 17 2019 07 13 --   https://rhythm.tums.ac.ir/index.php/jthc/article/view/1026 https://rhythm.tums.ac.ir/index.php/jthc/article/download/1026/894

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 6 11 Nooshin Peyman Department of Health Education and Health Promotion, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran. Fateme Shahedi Health Science Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Mahbubeh Abdollahi Department of Public Health, School of Health, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. AND Health Science Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Hassan Doosti Health Science Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Zohre Zadehahmad Health Sciences Research Center, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. AND Department of Public Health, School of Health, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran. 2018 10 22 2019 10 10 Background: Self-efficacy in self-care behaviors is an effective framework for measuring patients’ degree of ability to perform self-care behaviors that significantly affect their recovery process and quality of life. This study was designed to investigate the effects of education based on self-efficacy strategies on self-care behaviors in heart failure patients. Methods: A semi-experimental study was conducted on 80 heart failure patients divided into 2 equal groups of test and control. The intervention group received three 60-minute practical and theoretical training sessions based on self-care and self-efficacy strategies, while the control group received the usual care services. Self-care behaviors and self-efficacy were evaluated before training, shortly after training, and 3 months after the training program using the Sullivan self-efficacy questionnaire for heart failure patients and the European self-care behaviors questionnaires. Results: The mean age of the patients was 55.00±8.48 and 51.61±8.51 years in the intervention and control groups, respectively. Women comprised 73.7% (n=59) of the study population. The mean score for the self-care and self-efficacy questionnaires in the experimental group was 23.50±6.58 and 18.57±6.64, correspondingly, before the intervention, which increased to 42.64±6.74 (P<0.014) and 32.29±7.06 (P<0.001), respectively, shortly after the intervention. A significant improvement also occurred at 3 months’ follow-up (P<0.001). Self-care behaviors also revealed a positive correlation with self-efficacy shortly after the intervention (r=0.82, P<0.001) and 3 months after the intervention (r=0.85, P<0.001). Conclusion: The implementation of educational interventions based on self-efficacy strategies could have positive effects on health-promoting behaviors among heart failure patients. https://rhythm.tums.ac.ir/index.php/jthc/article/view/972 https://rhythm.tums.ac.ir/index.php/jthc/article/download/972/885

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 35 38 Arezoo Zorufian Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mahmoud Shirzad Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Narges Shahbazi Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Saheb Jam Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Zahra Rahnamoun Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Shapoor Shirani Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Tahereh Davarpasand Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. 2019 03 02 2019 12 14 Nowadays, the early diagnosis of tumoral diseases is more possible and accurate with multiple diagnostic imaging modalities such as chest X-ray, echocardiography, computed tomography, and magnetic resonance imaging, especially for cardiac tumors which are usually asymptomatic, even in large sizes. In cardiac masses, the patients’ presentations are non- specific and dependent on the tumor size and site as well as its compressive effect on the adjacent structures. On the other hand, the first and last signs could be sudden cardiac death. However, cardiac masses are either benign or malignant and metastatic in their malignant type, and their definite diagnosis is only possible by surgical tumor resection and tissue biopsy. In this paper, we describe an old patient with severe pericardial effusion and an unusual intrapericardial tumor in transthoracic echocardiography, representing a rare case of a giant ectopic thymoma after surgical resection and pathologic assessment. https://rhythm.tums.ac.ir/index.php/jthc/article/view/1049 https://rhythm.tums.ac.ir/index.php/jthc/article/download/1049/893

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 04 12 41 42 EN Ensiyeh Jenabi Autism Spectrum Disorders Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Salman Khazaei Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran. 2018 08 13 2019 07 23 None https://rhythm.tums.ac.ir/index.php/jthc/article/view/950 https://rhythm.tums.ac.ir/index.php/jthc/article/download/950/892

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 12 17 EN Nazila Shahmansouri Psychosomatic Medicine Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mehrdad Salehi Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Ali Reza Bakhshandeh Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Roya Sattarzadeh Badkoubeh Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Masoumeh Lotfi- Tokaldani Research Department, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. Ahmad Ali Noorbala Psychosomatic Medicine Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Azadeh Mashayekhi Psychosomatic Medicine Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2019 03 01 2019 05 22 Background: Heart transplantation is a major procedure which imposes high emotional stress on patients. Illness perception (IP) is a psychological issue which affects psychological adjustment after transplantation. This study aimed to investigate the association between IP and emotional status in Iranian post-heart transplantation patients. Methods: The present cross-sectional study, conducted between 2018 and 2019 in Imam Khomeini Hospital, Tehran, Iran, recruited 121 post-heart transplantation patients. IP was measured using the Brief Illness Perception Questionnaire (B-IPQ), and emotional status was measured using the Hospital Anxiety and Depression Scale. The association between IP and depression/anxiety was assessed. Results: Men comprised 80.2% of the study population. The mean age of the participants was 43.9±12.95 years. Definite caseness for depression and anxiety was reported in 11.6% and 18.2% of the participants, respectively. The median score of IP was 55. The association between anxiety and IP in total IP and the 3 dimensions of IP was statically significant (P=0.015, P=0.018, P=0.002, and P=0.023 for the cognition, emotion, and understanding dimensions and the total IPQ, respectively). Additionally, the association between depression and IP was significant (P=0.001, P=0.029, and P=0.002 for the cognition and emotion dimensions and the total IPQ, correspondingly, except for the understanding dimension). Furthermore, lower levels of anxiety in the patients showed a greater impact on IP than did depression. Conclusion: There was a significant association between IP and depression and anxiety in our study population. Therefore, the diagnosis and management of anxiety and depression in heart transplantation patients may improve IP. The cross-sectional design of the present study precluded an investigation of the causality between IP and emotional status. https://rhythm.tums.ac.ir/index.php/jthc/article/view/1047 https://rhythm.tums.ac.ir/index.php/jthc/article/download/1047/886

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 27 30 Zahra Khajali Department of Cardiovascular Medicine, Shaheed Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran. Majid Maleki Department of Cardiovascular Medicine, Shaheed Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran. Bahram Mohebbi Department of Cardiovascular Medicine, Shaheed Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran. Maryam Aliramezany Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran. 2018 10 19 2019 07 06 Congenitally corrected transposition of the great arteries (cc-TGA) is a rare congenital abnormality that occurs in 1 per 33000 live births. This abnormality comprises nearly 0.05% of all congenital heart defects, with at least 90% of cc-TGA patients having associated cardiac defects; some of these associated defects are, however, very rare. In this case report, we describe a 22-year-old man who referred to our hospital for the evaluation of hypertension and cardiac murmurs. Via echocardiography and catheterization, the patient was finally diagnosed with cc-TGA, bicuspid aortic valve, and coarctation of the aorta. He underwent successful percutaneous transarterial coarctoplasty without any complications at early and 6 months’ follow-up visits. https://rhythm.tums.ac.ir/index.php/jthc/article/view/971 https://rhythm.tums.ac.ir/index.php/jthc/article/download/971/888

Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 15 1 2020 01 29 18 26 EN Mojdeh Pakbaz School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Marziyeh Pakbaz Department of Cardiovascular Diseases, Hazrat‐e Rasool General Hospital, Iran University of Medical Sciences, Tehran, Iran. 2018 08 01 2019 11 10 Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multi-systemic vasculitis, with cardiac involvement being one of its most serious manifestations. We aimed to systematically review and analyze the limited case reports of EGPA with cardiac involvement. Methods: Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we performed a systematic literature search for the case reports of EGPA with cardiac involvement in the MEDLINE database from 2011 until 2018. For each case, clinical data including sex, age, clinical presentation, electrocardiographic and cardiac imaging findings, the type of cardiac involvement, the available laboratory data (cardiac biomarkers, white blood cell count, eosinophilic count, erythrocyte sedimentation rate, C-reactive protein, and antineutrophil cytoplasmic antibody positivity), therapeutic regimen, and the outcome of the patients were collected and analyzed. Results: A total number of 62 cases were included. The mean age was 48.29±15.60 years, and 51.6% were male. All the cases were in the active disease state. Cardiac symptoms, electrocardiographic abnormalities, abnormal biomarkers, and abnormal echocardiography were detected in 82.3%, 68.5%, 77.4%, and 96.8%, respectively. Cardiac magnetic resonance was done in 46.8% of the patients, and it was abnormal in all. The most common abnormal findings in echocardiography were systolic left ventricular dysfunction (83.9%) and pericardial effusion (37.1%). The most common type of clinical presentation was clinical heart failure (51.6%). Only 6.5% of the patients presented with tamponade. The overall prognosis was good. Conclusion:  Any part of the heart could be involved by EGPA. The results emphasize the necessity of in-depth cardiac evaluation in these patients. https://rhythm.tums.ac.ir/index.php/jthc/article/view/946 https://rhythm.tums.ac.ir/index.php/jthc/article/download/946/887